Accolate



 
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Accolate - Basic Information

 

Indication of Accolate:

Accolate is a treatment of asthma

Action of Accolate:

-Act by antagonizing airway smooth muscle contraction and inflammation

Dose Advice of Accolate:

-20 mg twice daily at least 1 hour before or 2 hours after meals -May be increased up to 40 mg twice daily Pregnancy: -Limited experience. ADEC category B1 Lactation: -Limited experience, should be safe to use

Schedule of Accolate:

Schedule 4

Common side effects of Accolate:

-Headache -Abdominal pain -Diarrhoea -Drug interactions: -Warfarin: increased INR (monitor INR) -Theophylline: possible increase in theophylline concentration (monitor theophylline concentration) -Erythromycin: Decreases Zafirlukast concentration (may require larger dose of Zafirlukast)

Uncommon side effects of Accolate:

-Hepatitis (avoid use in hepatic impairment) -Churg-Strauss syndrome -Allergic reactions including urticaria, angioedema and anaphylaxis


GN: Zafirlukast

Con: Headache