Indication of EES:
Erythromycin is useful in the treatment of the following infections when they are caused by susceptible organisms: -upper and lower respiratory tract infections-skin and soft tissue infections-primary syphilis-erythrasma-acne (in combination with other agents)It can be used for the prevention of heart valve infection in patients with rheumatic or valvular heart disease undergoing dental procedures or upper respiratory tract surgery.EES can be used to treat sexually transmitted diseases such as gonorrhoea and Chlamydia. It can also be used to treat non-genital Chlamydial infections such as trachoma or conjunctivitis.Erythromycin is useful in combination with antitoxin in the treatment of diphtheria.It is also useful in eliminating the whooping cough bug from the throat, which prevents spread of the disease.EES can be used for the prevention of tetanus in people hypersensitive to penicillin. This is not 100% reliable, so wounds should be regularly examined
Action of EES:
Erythromycin is an antibiotic from the macrolide family. At low concentrations it immobilises and prevents bacteria from multiplying, and at high concentrations it kills them. Erythromycin works by binding to a specific site on susceptible bacteria and inhibiting production of proteins. It is active against a variety of organisms, including the well-known Staphylococcus aureus. It is also active against Streptococcus pneumoniae and Haemophilus influenzae, two important causes of respiratory tract infections. Erythromycin also has activity against the bugs that cause: -diphtheria-tetanus-gonorrhoea-whooping cough-Legionnaire
