Indication of healthsense Isosorbide Mononitrate:
Prophylaxis for angina pectoris
Action of healthsense Isosorbide Mononitrate:
Isosorbide mononitrate reduces the end diastolic pressure and volume leading to an improvement in the subendocardial blood flow. The net result is reduced workload for the heart by producing venous and arterial dilatation and an improvement in oxygen supply. Natural initiator of vascular relaxation is endothelium derived relaxing factor, which has the characteristics of nitric oxide. Organic nitrates are metabolised to nitric oxide and they are thought to be the physiological substitute for endothelium derived relaxing factor.
Dose Advice of healthsense Isosorbide Mononitrate:
One 60mg tablet daily Dose may be increased to two tablets (120mg) daily - both tablets need to be taken at the same time. However GenRx Isosorbide mononitrate Sustained Release tablets should not be administered twice daily. The Sustained Release tablets should not be crushed or chewed and should be swallowed whole with fluid. GenRx Isosorbide mononitrate Sustained Release tablets are not recommended for management of acute attacks of angina pectoris. Most common symptom of overdose is a pulsing headache. Emesis should be induced and then activated charcoal should be administered In cases of severe hypotension, patient should be placed in supine position with legs raised
Schedule of healthsense Isosorbide Mononitrate:
S4
Common side effects of healthsense Isosorbide Mononitrate:
Headache
Uncommon side effects of healthsense Isosorbide Mononitrate:
-Tiredness -Sleep disturbance -Gastrointestinal disturbances -Hypotension -Poor appetite -Nausea -Tachycardia -Heartburn -Vertigo
