Imdur Durules



 
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Imdur Durules - Basic Information

 

Indication of Imdur Durules:

Prophylaxis for angina.

Action of Imdur Durules:

Isosorbide mononitrate reduces the end diastolic pressure and volume leading to an improvement in the subendocardial blood flow. The net result is reduced workload for the heart by producing venous and arterial dilatation and an improvement in oxygen supply. Natural initiator of vascular relaxation is endothelium derived relaxing factor, which has the characteristics of nitric oxide. Organic nitrates are metabolised to nitric oxide and they are thought to be the physiological substitute for endothelium derived relaxing factor.

Dose Advice of Imdur Durules:

One 60mg tablet daily. Dose may be increased to two tablets (120mg) daily - both tablets need to be taken at the same time. Isosorbide mononitrate Sustained Release tablets should not be administered twice daily. The Sustained Release tablets should not be crushed or chewed and should be swallowed whole with fluid. Isosorbide mononitrate Sustained Release tablets are not recommended for management of acute attacks of angina pectoris. Most common symptom of overdose is a pulsing headache. Emesis should be induced and then activated charcoal should be administered In cases of severe hypotension, patient should be placed in supine position with legs raised

Schedule of Imdur Durules:

S4

Common side effects of Imdur Durules:

Headache.

Uncommon side effects of Imdur Durules:

Tiredness Sleep disturbanceGastrointestinal disturbances Hypotension Poor appetiteNausea Tachycardia Heartburn Vertigo

Diseases treated by Imdur Durules:

Pulmonary Heart Disease - Cor Pulmonale


GN: Isosorbide mononitrate

Con: angina