Imuran
Imuran - Basic Information
Indication of Imuran:
Azathioprine is used for the following indications: Immunosuppression in: Severe rheumatoid arthritis.Systemic lupus erythematosus.Dermatomyositis and polymyositis.Autoimmune chronic active hepatitis.Pemphigus vulgaris.Polyarteritis nodosa.Autoimmune haemolytic anaemia.Autoimmune thrombocytopenic purpura. Prevention of organ transplant rejection.Inflammatory Bowel Disease.Behcets syndrome.Action of Imuran:
Azathioprine suppresses the immune system and reduces inflammation.Dose Advice of Imuran:
The hematologic response should be monitored to guide dosing. Bone marrow suppression will limit the dose that can be given.The initial recommended dose is 2-3 mg/kg once daily given either orally or intravenously.Maintenance dosing is 1-3 mg/kg or the minimum dose required to control the disease or prevent transplant rejection.Renal impairment: Dose reductions may be necessary.Hepatic impairment: Dose reductions may be necessary.Schedule of Imuran:
S4Common side effects of Imuran:
Increased susceptibility to viral, fungal and bacterial infections.Hair loss.Nausea and vomiting.Diarrhoea.Loss of appetite.Mouth ulceration.Inflammation of the Oesophagus.Skin rashes.Anaemia.Uncommon side effects of Imuran:
Hepatitis.Severe anaemia. Pancreatitis.Allergic reactions such as: Fevers.Rigors.Muscle and joint aches.Rash.Cough.Shortness of breath.Low blood pressure.Abnormal liver function.Abnormal heart rhythm.Kidney dysfunction.Increased risk of skin cancers and certain other types of cancer.Diseases treated by Imuran:
Crohns disease (Inflammatory Bowel Disease) (Crohns Disease (Inflammatory Bowel Disease)) Lupus Nephritis Polymyositis Rheumatoid Arthritis Sarcoidosis Ulcerative Colitis (Inflammatory Bowel Disease)Treatments associated with Imuran:
Immunosuppressants in organ transplantation (Immunosuppressants in organ transplantation)Con: Dermatomyositis
Cla: Immunosuppressants in organ transplantation