Methadone Syrup



 
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Methadone Syrup - Basic Information

 

Indication of Methadone Syrup:

Maintenance of opioid dependenceOpioid detoxification

Action of Methadone Syrup:

Methadone is an opioid receptor agonist. Reduces withdrawal symptoms and craving for opioids in opioid dependence

Dose Advice of Methadone Syrup:

Methadone maintenance: Initially 20-30mg daily then increase by small increments according to local protocols, to a maintenance dose around 60-80mg daily in most patientsMethadone to achieve opioid abstinence: Initially 20-30mg daily in 1 or 2 divided doses, then reduce gradually over 7-21 days.

Schedule of Methadone Syrup:

S8

Common side effects of Methadone Syrup:

Type and severity of adverse effects depend on dosage and circumstances of use. NauseaVomitingDrowsinessDry mouthMiosisOrthostatic hypotensionConstipation

Uncommon side effects of Methadone Syrup:

ImpotenceConfusionHallucinationsDeliriumUrticariaItchHypothermiaBradycardia or tachycardiaRaised intracranial pressureUreteric or biliary spasmMuscle rigidityUrinary retention

Diseases treated by Methadone Syrup:

Opioid Induced Hyperalgesia


GN: Methadone hydrochloride

Con: Opioid Induced Hyperalgesia