Neo-Mercazole



 
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Neo-Mercazole - Basic Information

 

Indication of Neo-Mercazole:

Neo-Mercazole is a medicine used to decrease the amount of thyroid hormones produced by the thyroid gland. It is used to treat conditions resulting in an overactive thyroid gland (hyperthyroidism).

Action of Neo-Mercazole:

Neo-Mercazole works by decreasing the amount of thyroid hormones produced by the thyroid gland. Iodine is a chemical used by the thyroid gland in the formation of thyroid hormones. Iodine must be converted in the body to a useable form before it may be combined with other components to form thyroid hormones. Neo-Mercazole acts to prevent the conversion of iodine to its usable form. It also acts to block the combination of converted iodine with other components to form thyroid hormones. This therefore results in decreased production of thyroid hormones. As a result, Neo-Mercazole is useful in the treatment of conditions where excessive amounts of thyroid hormones are being produced (hyperthyroidism).

Dose Advice of Neo-Mercazole:

Dose may be taken with or without food.ADULTS: Initially. Mild cases, 15 to 20mg/day in divided doses. Moderate cases, 30mg/day in divided doses. Severe cases, 40 to 45mg (maximum 60mg) per day in divided doses. Maintenance dosing: Once symptoms are controlled the dosage can then be decreased to one that can be maintained This is usually between 10 and 15mg per day.Changeover from thiouracils: Treatment of 50mg of methylthiouracil or propylthiouracil can be replaced with 5mg of Neo-Mercazole.

Schedule of Neo-Mercazole:

S4

Common side effects of Neo-Mercazole:

Generally there are no side effects in patients on doses of Neo-Mercazole of less than 20mg per day. The most common side effects in patients on higher doses include the following: NauseaHeadacheAching jointsStomach upset

Uncommon side effects of Neo-Mercazole:

Some people can experience the following side effects when taking Neo-Mercazole. You should discuss these with your doctor. ItchingSkin rashesHair lossBone marrow depressionJaundiceBlood disorders

Diseases treated by Neo-Mercazole:

Hyperthyroidism


GN: Carbimazole

Con: Hyperthyroidism