Nolvadex, Nolvadex-D



 
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Nolvadex, Nolvadex-D - Basic Information

 

Indication of Nolvadex, Nolvadex-D:

Tamoxifen is used in the palliative treatment of breast cancer that has been shown to express oestrogen receptors.

Action of Nolvadex, Nolvadex-D:

Tamoxifen is a non-steroidal anti-oestrogen. It probably works by binding to oestrogen receptors, and this inhibits the effects of endogenous oestrogen. Many breast cancers have oestrogen receptors and therefore have their growth stimulated by the presence of oestrogen. By inhibiting oestrogen, Tamoxifen inhibits tumour growth.

Dose Advice of Nolvadex, Nolvadex-D:

Initial dose is 20mg once daily. If no improvement is seen within one month, increase to 40mg daily.

Schedule of Nolvadex, Nolvadex-D:

S4

Common side effects of Nolvadex, Nolvadex-D:

hot flushesnauseavomiting

Uncommon side effects of Nolvadex, Nolvadex-D:

fluid retention vaginal bleedingvaginal dischargevaginal itchingtumour paintumour flarelightheadednessheadachesskin rashhair lossIncreased occurrence of endometrial (lining of uterus) changes have been reported These range from polyps to cancer. Unusual vaginal bleeding should be immediately reported to your doctor.Visual changes may occur rarely.

Diseases treated by Nolvadex, Nolvadex-D:

Breast Cancer (Pre-Invasive Lobular Carcinoma; Lobular Carcinoma In Situ; LCIS)


GN: Tamoxifen citrate

Con: breast cancer