Panadeine

Indication of Panadeine:

Temporary relief of mild to moderate pain and fever.

Action of Panadeine:

Panadeine contains two active ingredients- paracetamol and codeine, which work in different ways to reduce pain. Paracetamol has painkilling as well as antipyretic (anti-fever) effects by preventing the production of chemical substances called prostaglandins, which are responsible for the pain and inflammatory response. Codeine is an opioid analgesic and works by activating opioid receptors in nervous system to produce painkilling effects. It also acts at the level of the spinal cord to prevent the transmission of pain impulses.

Dose Advice of Panadeine:

Each tablet of Panadeine contains 500 mg paracetamol and 8mg codeine phosphate.Can be taken with or without food. Adults: 1-2 tabs 4 hourly; max. 8 tabs daily

Schedule of Panadeine:

12s, 24s: S2 Other pack sizes: S3, except NSW: S2

Common side effects of Panadeine:

As with any other medication, Panadeine can cause a number of side effects, most of which are likely to be minor and cease when the medication is stopped Codeine phosphate is known to cause a number of side effects including: Nausea and vomitingConstipation (chronic use)DizzinessDry mouthParacetamol is considered to have very few side effects when taken at normal doses.

Uncommon side effects of Panadeine:

Less common side effects include: hypersensitivity rashes feverblood abnormalities such as reduced numbers of white blood cells or platelets.

Diseases treated by Panadeine:

Carpal Tunnel Syndrome Cervical Root disorders (cervical spondylotic myelopathy & radiculopathy) Headache Somatoform disorders (Briquets syndrome) Tension headache Thoracic back pain (upper vertebral fractures/pain)

Symptoms associated with Panadeine:

Muscle cramps

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