Indication of Pitressin:
Pitressin is a medicine that reduces the amount of urine excreted by the body. Drugs such as this are known as antidiuretics. It is used to treat diabetes insipidus, a disease where you produce large amounts of dilute urine and are constantly thirsty.
Action of Pitressin:
Pitressin is similar to a naturally occurring hormone present in the body, known as antidiuretic hormone (ADH). ADH has two main effects on the body. It causes the kidney to retain water in the body, which helps to prevent excessive loss of water in the urine. Secondly, ADH causes narrowing of blood vessels (vasoconstriction), thereby limiting blood flow to a particular area of the body. In diabetes insipidus, the function of ADH is lost, causing an increase in water lost from the body through urine. Therefore Pitressin is used to treat this condition, as it mimicks the effect of ADH, acting on the kidney and preventing dehydration by excessive loss of water.
Dose Advice of Pitressin:
Pitressin can be administered via injection into the subcutaneous tissue (fat) or the muscle, or via spray or drops into the nose. Subcutaneous of intramuscular dosage should not exceed 0.75mL. ABDOMINAL SWELLING: Recommended dosage for the average postoperative patient is 0.25mL (5 units) by intramuscular or subcutaneous injection initially. This can be increased to 0.5mL for further injections if necessary. Injections can be given at 3 to 4 hourly intervals as needed ABDOMINAL RADIOGRAPHY: The recommended dose is two intramuscular or subcutaneous injections of 0.5mL each (10 units). These should be given at 2 hours and
