Vincristine sulfate injection

Indication of Vincristine sulfate injection:

Vincristine is a medication that is used in chemotherapy to treat a range of cancers, including acute leukaemia, Non-Hodgkins lymphoma, rhabdomyosarcoma of muscle, neuroblastoma, Wilms tumour, osteogenic sarcoma, Ewings sarcoma, squamous cell carcinoma of the cervix, breast cancer, malignant melanoma, oat-cell carcinoma of the lung and gynaecological tumours of childhood.

Action of Vincristine sulfate injection:

Vincristine slows the rate at which cancer cells divide by inactivating certain parts of the cell necessary for division to occur.

Dose Advice of Vincristine sulfate injection:

Vincristine is given as an injection. Your doctor or nurse will give the injection to you. You should tell your doctor or nurse if you experience any of the following when you have been given Vincristine: Any pain or unusual sensations ConstipationBleeding more than normalNumbness or tingling sensationsVincristine can sometimes make people more prone to infections. Your doctor will talk to you about this. If you think you may have an infection tell your doctor. Vincristine should not be given to pregnant women (Pregnancy Category D).

Schedule of Vincristine sulfate injection:

Schedule 4

Common side effects of Vincristine sulfate injection:

All medicines have side effects. Some side affects can be serious but most are mild. The following is a list of common side effects that occurred in more than 1% of people who were given Vincristine: Hair loss - (occurs in more than 20% of people) ConstipationMild nausea and vomitingTalk to your doctor if you experience any side effects.

Uncommon side effects of Vincristine sulfate injection:

The following is a list of uncommon side effects that occurred in less than 0.1% of people who were given Vincristine injection. Do not be alarmed by this list. You may not experience any side effects. Hearing problemsBalance difficultiesSeizuresConsult your doctor if you experience any of the above symptoms, or any other unusual or abnormal symptoms that concern you.

Reference:

Australian Medicines Handbook. Vincristine .[Monograph online]AMH Pty Ltd 2007[cited December 13, 2007] http: //www.amh.net.auVincristine. MIMs Online. [Monograph online]MIMS Australia Pty Ltd 2007. [Cited December 13, 2007] http: //www.mims/com.auLazo J, Gilman A, Brunton L, Parker K. Goodman & Gilmans the pharmacological basis of therapeutics. 11th ed New York: Mcgraw-Hill; 2005.

Diseases treated by Vincristine sulfate injection:

Hodgkins Lymphoma Medulloblastoma / Primitive Neuroectodermal tumour (PNET)  (Medulloblastoma / Primitive Neuroectodermal tumour (PNET)) Multiple Myeloma Neuroblastoma

• Oncovin
• Vincristine sulfate injection

• Vincristine sulfate injection