Zantac



 
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Zantac - Basic Information

 

Indication of Zantac:

The use of Ranitidine is indicated in the following conditions: Peptic ulcer disease Gastro-oesophageal reflux disease Heartburn

Action of Zantac:

Zantac belongs to a class of drugs called histamine receptor antagonists. Its active ingredient, Ranitidine, works by decreasing the amount of acid the stomach produces.

Dose Advice of Zantac:

Peptic Ulcer Disease The initial recommended dose is 300 mg orally given as a single evening dose for 4–8 weeks or 50 mg intravenously or intramuscularly given every 6–8 hours. Maintenance dosing is 150–300 mg orally given as a single evening dose. Gastro-Oesophageal Reflux Disease 300 mg orally given as a single evening dose Prevention of stress ulcer The initial dose is 50 mg intravenously given slowly An intravenous infusion of 125–250 micrograms/kg/hour should be continued until risk factors for stress ulcer are removed Heartburn 150 mg orally twice a day for 4–8 weeks. Children 2–4 mg/kg orally twice daily up to a maximum dose of 300 mg a day. 1 mg/kg intravenously every 6–8 hours up to a maximum dose of 50 mg.

Schedule of Zantac:

S4

Common side effects of Zantac:

Headache Fatigue Dizziness Confusion (especially in elderly people) Diarrhoea Constipation Rash

Uncommon side effects of Zantac:

Development of breast tissue in males Decreased libido Impotence Reversible involuntary movement

Diseases treated by Zantac:

Zollinger-Ellison Syndrome (Gastrinoma)

Symptoms associated with Zantac:

Heartburn Managing the Symptoms of GORD


GN: Ranitidine hydrochloride

Con: Zollinger-Ellison Syndrome (Gastrinoma)